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Symbol Name ID |
Notch1
notch 1 MGI:97363 |
| Darker colors indicate more annotations |
| Human Phenotypes | Portal vein thrombosis |
Portal hypertension |
Cirrhosis |
Congenital hepatic fibrosis |
| Disease(s) Associated with NOTCH1 | ||||
| Adams-Oliver syndrome |
| Mouse Phenotypes | dilated liver sinusoidal space |
increased liver weight |
chronic liver inflammation |
abnormal liver morphology |
abnormal hepatic cord morphology |
abnormal liver parenchyma morphology |
abnormal liver lobule morphology |
hepatic steatosis |
pale liver |
increased cholangiocarcinoma incidence |
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| Availability | Mouse Genotype | ||||||||||
| Albtm1(cre/ERT2)Mtz/Alb+ Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+ (conditional) |
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| Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+ Tg(Adipoq-cre)1Evdr/0 (conditional) |
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| Notch1tm2Rko/Notch1tm3(cre)Rko (conditional) | |||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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